Mice discovered accidentally at the Wistar Institute in Pennsylvania have the seemingly miraculous ability to regenerate like a salamander, and even regrow vital organs.
Researchers systematically amputated digits and damaged various organs of the mice, including the heart, liver and brain, most of which grew back.The results stunned scientists because if such regeneration is possible in this mammal, it might also be possible in humans. The researchers also made a remarkable second discovery: When cells from the regenerative mice were injected into normal mice, the normal mice adopted the ability to regenerate. And when the special mice bred with normal mice, their offspring inherited souped-up regeneration capabilities. The mice, known as the MRL strain, were specially bred to develop lupus.
But researchers don't know why exactly the animals' injuries heal so well. "If we identified the molecules that allow mice that don't regenerate to regenerate ... and I think we could be close to doing that, then I think the next step is to consider what these molecules would do in individuals," said Ellen Heber-Katz, a professor of molecular and cellular oncogenesis at Wistar, located on the University of Pennsylvania campus in Philadelphia.
http://www.wired.com/news/medtech/0,1286,68962,00.html?tw=wn_tophead_1